University of California-San Diego · NeuroscienceSpinal Cord Recovery Laboratory
Mark H. Tuszynski · La Jolla, California
Research Focus
Dr. Mark H. Tuszynski's lab focuses on understanding and promoting recovery after spinal cord injuries in primates. Using advanced techniques, the lab investigates how injured spinal neurons can regenerate and form new connections, which could lead to improved voluntary motor control. Their research aims to identify optimal time points for intervention and to enhance the effectiveness of neural stem cell therapies for spinal cord healing.
spinal cord injuryneural regenerationcorticospinal tractRNA sequencingtherapeutic interventionprimate connectomeneural stem cellsaxon regenerationmotor control
Research Aims
4AIM 01Investigate the transcriptional changes in injured corticospinal neurons in primates after spinal cord injury.
AIM 02Determine the optimal time window for therapeutic interventions following spinal cord injury.
AIM 03Trace the corticospinal projections to understand their targets in the spinal cord.
AIM 04Enhance the formation of neural relays across spinal cord injuries using stem cell grafts.
Skills the Lab Values
RNA sequencingviral vector techniquesaxon tracinganimal modelsneural stem cell culturedata analysisimmunohistochemistrybehavioral assessments in animalsmicroscopy
Output against the department
Publications349top 19% of dept.125th of 671
this lab
most publishedleast published
Citations33ktop 11% of dept.75th of 671
this lab
most citedleast cited
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