Georgetown University · BiologyThe Remyelination Initiative
Jeffrey K Huang · Washington, District of Columbia
Research Focus
Dr. Jeffrey K Huang's lab studies how the immune system interacts with nerve cells to promote healing in conditions like multiple sclerosis, where nerve insulation is damaged. His research involves manipulating specific molecules to encourage nerve cells to repair themselves and improve patient outcomes. By understanding these interactions better, his work aims to develop new treatments that could help individuals suffering from demyelinating diseases.
multiple sclerosisCNS remyelinationmicrogliamacrophagesimmune regulationprotein analysismetabolismtherapeutic strategies
Research Aims
3AIM 01Investigate how inhibiting Slc7a5 affects microglial activity in demyelinated lesions.
AIM 02Analyze the metabolic and proteomic characteristics of pro-regenerative myeloid cells after Slc7a5 deletion.
AIM 03Identify factors produced by microglia/macrophages that regulate the remyelination process when Slc7a5 is inhibited.
Skills the Lab Values
PCRcell culturemouse modelsproteomicsmetabolomicsWestern blotflow cytometrygene editingimmunofluorescencedata analysis
Output against the department
Publications82bottom 25% of dept.771st of 1,033
this lab
most publishedleast published
Citations3.9kbottom 30% of dept.722nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.