University of Utah · PharmacologyKoh Cancer Lab
Mei Yee Koh · Salt Lake City, Utah
Research Focus
Dr. Mei Yee Koh's research lab focuses on understanding how obesity influences liver cancer development, particularly through a protein called HAF. They explore the links between metabolic diseases, like fatty liver disease, and hepatocellular carcinoma, aiming to identify new ways to prevent or treat this aggressive cancer. By studying how HAF functions at the molecular level, the lab hopes to uncover new biomarkers and therapeutic targets that can improve outcomes for patients with liver cancer.
Hepatocellular carcinomaobesityfatty liver diseasemolecular pathwaystumor suppressor role
Research Aims
3AIM 01Investigate the molecular mechanisms by which HAF activates the NF-kB pathway.
AIM 02Determine how HAF protects liver cells from excessive cell death during inflammation.
AIM 03Analyze HAF expression in patient samples to correlate it with liver cancer progression.
Skills the Lab Values
cell culturemouse modelsRNA interferenceWestern blotgenomic analysisimmunohistochemistrybiostatisticsprotein interaction assaysqPCR
Output against the department
Publications102bottom 26% of dept.338th of 462
this lab
most publishedleast published
Citations3.0kbottom 23% of dept.357th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.