Boston University · PharmacologyChronic Pain Research Group
Venetia Zachariou · Boston, Massachusetts
Research Focus
Dr. Venetia Zachariou's lab at Boston University Medical Campus focuses on understanding chronic pain mechanisms, specifically looking at a protein called RGS4 that influences nerve signals. By studying how RGS4 functions in different types of nerve cells, the lab aims to identify new targets for pain management, potentially leading to safer and more effective treatments for people suffering from neuropathic pain.
chronic painneuropathic painRGS4G protein signalingnerve injury
Research Aims
5AIM 01Investigate the role of RGS4 in sensory aspects of neuropathic pain.
AIM 02Explore the impact of RGS4 expression on emotional manifestations of pain.
AIM 03Examine gene expression changes in response to nerve injury with a focus on RGS4.
AIM 04Determine specific neuronal mechanisms involving RGS4 in pain pathways.
AIM 05Develop interventions targeting RGS4 for improved pain management.
Skills the Lab Values
mouse modelsbiochemical assaysRNA sequencingbehavioural studiesgenetic modificationtissue culturebiosensorsmolecular cloningdata analysis
Output against the department
Publications146bottom 41% of dept.270th of 462
this lab
most publishedleast published
Citations7.6ktop 48% of dept.221st of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.