Colorado School of Mines · ChemistryFluorescent Insights Lab
Dylan W Domaille · Golden, Colorado
Research Focus
Dr. Dylan W. Domaille's research lab at the Colorado School of Mines focuses on the development of advanced fluorescent probes. These probes help visualize reactive oxygen and nitrogen species in living cells, which play critical roles in various health conditions, including cancer and heart disease. The lab aims to create a new toolkit for imaging, allowing for better understanding of how these species contribute to inflammation and other cellular processes. As part of their work, the lab emphasizes training undergraduates to engage in collaborative biomedical research.
reactive oxygen speciesfluorescent probescell imagingbioengineeringinflammationoxidative metabolitesdisease pathology
Research Aims
5AIM 01Develop new fluorescent probes for multi-color imaging of peroxynitrite in cells.
AIM 02Understand the dynamics of reactive oxygen and nitrogen species in redox biology.
AIM 03Investigate the structure-function relationships of diazaborine compounds.
AIM 04Apply imaging probes in cell culture models of macrophages.
AIM 05Train undergraduate students in advanced imaging techniques and collaborative research.
Skills the Lab Values
fluorescence microscopychemical synthesismolecular probe designcell cultureimaging techniquesspectral analysisdata interpretationorganic chemistry principles
Output against the department
Publications70bottom 13% of dept.188th of 216
this lab
most publishedleast published
Citations7.0kbottom 44% of dept.121st of 216
this lab
most citedleast cited
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