University of North Carolina at Chapel Hill · Biomedical EngineeringRadiochemistry and PET Imaging Lab
Zibo Li · Chapel Hill, North Carolina
Research Focus
Professor Zibo Li's lab focuses on developing new techniques for labeling biomolecules with fluorine-18, a radioactive isotope used in medical imaging. The research aims to create efficient tools for producing radiolabeled agents that can improve the visualization of drug distribution in the brain and enhance medical imaging technologies. This work could significantly impact the fields of drug discovery and cancer imaging.
radiochemistryPET imagingfluorine-18bioconjugationtetrazine ligation
Research Aims
3AIM 01Develop improved methods for synthesizing 18F-labeled trans-cyclooctenes.
AIM 02Create a rapid method for preparing 18F-labeled tetrazine reporters.
AIM 03Validate the utility of new 18F-TCO and 18F-tetrazine compounds for brain permeability studies.
Skills the Lab Values
radiochemistry techniquesprotein labelingorganic synthesisphotochemistryin vitro assay development
Output against the department
Publications557top 13% of dept.76th of 595
this lab
most publishedleast published
Citations16ktop 23% of dept.138th of 595
this lab
most citedleast cited
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