Ohio State University-Main Campus · PhysiologyMitochondrial Cardiovascular Research Unit
Dmitry A Terentyev · Columbus, Ohio
Research Focus
Dr. Dmitry Terentyev's lab at Ohio State University focuses on understanding how mitochondrial dysfunction leads to dangerous heart rhythm problems. They study the relationship between mitochondria, calcium signaling, and heart health, particularly under stress. The lab aims to find ways to improve heart function and reduce the risk of fatal arrhythmias, especially in patients with specific genetic conditions or heart diseases.
mitochondriacalcium signalingcardiac arrhythmiaselectronic transport chainreactive oxygen speciesheart failurecatecholaminergic polymorphic ventricular tachycardiabioenergeticssex differencesmolecular targets
Research Aims
4AIM 01Investigate how RyR2 hyperactivity alters mitochondrial function in cardiac cells.
AIM 02Determine the role of COX7RP in mitochondrial dysfunction related to arrhythmias.
AIM 03Explore sex differences in mitochondrial bioenergetics and arrhythmic risk.
AIM 04Identify therapeutic targets to improve calcium handling in diseased hearts.
Skills the Lab Values
cell cultureanimal modelsPCRWestern blotimmunofluorescence microscopyelectrophysiologybiochemical assaysgenetic manipulationdata analysis in Pythonflow cytometry
Output against the department
Publications323top 15% of dept.42nd of 286
this lab
most publishedleast published
Citations7.6ktop 43% of dept.123rd of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.