Ohio State University-Main Campus · Microbiology & ImmunologyChronic Infection Research Lab
Daniel J Wozniak · Columbus, Ohio
Research Focus
Dr. Daniel J. Wozniak's lab at Ohio State University focuses on understanding the complex relationships between harmful bacteria and how they affect chronic infections, particularly in patients with cystic fibrosis. By studying the interactions between two common pathogens, Pseudomonas aeruginosa and Staphylococcus aureus, the lab aims to develop new treatments using bacteriophages, which are viruses that can kill bacteria. The goal is to find better ways to treat difficult-to-heal infections, especially those resistant to traditional antibiotics.
Pseudomonas aeruginosaStaphylococcus aureusbacteriophage therapypolymicrobial infectionchronic wound infectionbiofilmantibiotic resistanceimmune response
Research Aims
3AIM 01Investigate the antagonistic interactions between Pseudomonas aeruginosa and Staphylococcus aureus.
AIM 02Develop phage therapies to target multidrug resistant bacteria in wound infections.
AIM 03Explore how prior infections impact the immune response to subsequent infections.
Skills the Lab Values
bacteriophage isolationmacrophage cell cultureanimal modelsantibiotic susceptibility testingpolyvalent phage applicationsin vitro infection assaysmetabolic profilingbiofilm assessmentmolecular cloning
Output against the department
Publications272top 19% of dept.94th of 486
this lab
most publishedleast published
Citations22ktop 16% of dept.80th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.