Johns Hopkins University · NeuroscienceCenter for Sensory Adaptation Research
Hey-Kyoung Lee · Baltimore, Maryland
Research Focus
Dr. Hey-Kyoung Lee's research lab focuses on understanding how the brain adapts to sensory loss, especially in cases of vision and audition. By investigating neural circuits and synaptic mechanisms in the adult brain, the lab aims to reveal how one sense can compensate for another following deprivation. This work has implications for developing therapies to enhance sensory function in individuals with sensory impairments.
crossmodal plasticityneural circuitssensory deprivationauditory processingvisual processingsynaptic plasticityadult brainoptogeneticspharmacogenetics
Research Aims
3AIM 01Investigate how visual deprivation alters corticothalamic circuit function in adult mice.
AIM 02Evaluate the impact of visual deprivation on auditory feedforward pathways.
AIM 03Determine changes in sound encoding in corticothalamic neurons following sensory deprivation.
Skills the Lab Values
optogeneticsmultifoton Ca2+ imagingauditory behavior taskselectrophysiologyanimal modelscircuit analysisneuropharmacologydata analysis with Pythonhistologyimmunohistochemistry
Output against the department
Publications107bottom 37% of dept.423rd of 671
this lab
most publishedleast published
Citations12ktop 35% of dept.232nd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.