New York University · Microbiology & ImmunologyBacterial RNA Dynamics Lab
Joel G Belasco · New York, New York
Research Focus
Professor Joel G. Belasco's lab at New York University School of Medicine focuses on understanding how bacterial messenger RNA (mRNA) is degraded. This research is crucial for determining how gene expression is regulated in bacteria, especially in relation to their pathogenesis and response to antibiotics. The lab investigates unique RNA modifications and uses various molecular techniques to uncover how these processes affect bacteria in different environments.
mRNA degradationbacterial RNAgene expressionRNA cappingRNase Ebacterial pathogenesisantibiotic sensitivitycell physiology
Research Aims
5AIM 01Understand the principles governing mRNA degradation in bacteria.
AIM 02Elucidate the role of 5-terminal caps on bacterial mRNA lifetimes.
AIM 03Investigate the mechanism by which RNase E locates cleavage sites in mRNA.
AIM 04Explore the impact of the cellular environment on RNA degradation processes.
AIM 05Link bacterial RNA regulation to antibiotic sensitivity and pathogenesis.
Skills the Lab Values
molecular biology techniquesbiochemical assaysbiophysical analysisgenetic manipulationphylogenetic analysisRNA sequencingcell culturedata interpretation
Output against the department
Publications119bottom 45% of dept.265th of 486
this lab
most publishedleast published
Citations12ktop 31% of dept.149th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.