University of Kansas · Biomedical EngineeringAkhavan Lab
David Akhavan · Lawrence, Kansas
Research Focus
Dr. David Akhavan's lab at the University of Kansas Medical Center focuses on improving treatments for Glioblastoma Multiforme (GBM), a serious type of brain cancer. The lab is exploring innovative nanotechnology techniques to better deliver drugs to CAR T cells, which are designed to specifically target and kill cancer cells. Their research aims to enhance the effectiveness of this therapy while minimizing side effects for patients.
nanocarrier technologyCAR T cellsGlioblastoma Multiformeadoptive cell therapytumor microenvironment
Research Aims
5AIM 01Develop a new therapy to enhance CAR T cell treatments for GBM.
AIM 02Utilize nanocarriers to improve drug delivery to CAR T cells.
AIM 03Reduce the toxicity of treatments targeted at tumor environments.
AIM 04Investigate the immune-suppressive factors that affect CAR T cell efficacy.
AIM 05Enhance the therapeutic window of CAR T cells in solid tumors.
Skills the Lab Values
nanotechnologycell culturemouse modelsdrug delivery systemsflow cytometry
Output against the department
Publications116bottom 23% of dept.457th of 595
this lab
most publishedleast published
Citations3.1kbottom 23% of dept.457th of 595
this lab
most citedleast cited
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