University of Houston · EngineeringRetinal Health and Disease Unit
Muna I. Naash · Houston, Texas
Research Focus
Dr. Muna I. Naash's lab at the University of Houston focuses on understanding how certain genetic mutations lead to retinal diseases that can cause blindness. By using animal models, the lab explores the role of a protein called PRPH2 in the health of photoreceptor cells in the retina, aiming to identify therapeutic strategies that could help those affected by these conditions.
retinal degenerationphotoreceptor cellsPRPH2retinitis pigmentosagene therapyanimal modelsvasculaturemolecular biologytherapeutic strategies
Research Aims
5AIM 01Investigate the role of PRPH2 complexes in outer segment formation of photoreceptors.
AIM 02Explore the influence of ROM1 on photoreceptor disc morphogenesis.
AIM 03Identify protein partners that influence disease severity related to PRPH2 variants.
AIM 04Investigate variability in disease outcomes among patients with similar PRPH2 mutations.
AIM 05Develop novel therapeutic strategies to address PRPH2-associated phenotypes.
Skills the Lab Values
Mouse modelsElectroretinographyMolecular biology techniquesAdvanced imaging technologiesBiochemical assaysCell cultureProtein interaction studiesCRISPRAntisense oligonucleotides
Output against the department
Publications233top 39% of dept.109th of 278
this lab
most publishedleast published
Citations6.8kbottom 49% of dept.141st of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.