University of Pennsylvania · NeuroscienceThe Axon Connection Lab
Greg J. Bashaw · Philadelphia, Pennsylvania
Research Focus
Dr. Greg J. Bashaw's lab studies how neurons form connections in the brain and spinal cord, focusing on a specific receptor that guides the growth of nerve fibers. By investigating the mechanisms of this receptor, the lab aims to uncover insights into developmental disorders and potential treatments for nerve damage. Their research could contribute to a better understanding of how the nervous system develops and heals after injury.
axon guidanceneural developmentDCC receptorNetrin signalingneuronal morphology
Research Aims
3AIM 01Investigate how DCC signaling influences axon guidance during neural development.
AIM 02Identify the proteins that interact with the DCC receptor to understand its function.
AIM 03Explore the changes in gene expression regulated by DCC in neurons.
Skills the Lab Values
molecular biology techniquesRNA sequencingcell culturein vivo imagingproteomicsgenetic manipulationbioinformaticsWestern blotimmunofluorescence
Output against the department
Publications79bottom 22% of dept.519th of 671
this lab
most publishedleast published
Citations4.1kbottom 31% of dept.464th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.