Icahn School of Medicine at Mount Sinai · NeuroscienceRudebeck Lab
Peter Rudebeck · New York, New York
Research Focus
Dr. Peter Rudebeck's lab focuses on understanding the brain's wiring and communication in relation to mood and learning. They study how deep brain stimulation targeting white matter can help treat psychiatric disorders and investigate the neural circuit mechanisms underlying how we learn from rewards and punishments. By using techniques in primate models, they aim to reveal how brain pathways can be modified to enhance emotional and cognitive functions.
deep brain stimulationwhite matterneural circuitsaffective learningprimate modelspsychological disordersfunctional connectivitymicroscopyneurophysiologycomputational modeling
Research Aims
5AIM 01Establish the anatomical mechanisms of deep brain stimulation on white matter.
AIM 02Determine the functional effects of white matter deep brain stimulation on mood disorders.
AIM 03Investigate how bottom-up processes influence reward-based learning.
AIM 04Explore the impact of top-down influences on affective learning in the brain.
AIM 05Characterize the neural communication pathways between the PFC and amygdala during learning.
Skills the Lab Values
deep brain stimulationresting-state fMRIdiffusion MRIneural recordingsconfocal microscopyelectron microscopychemogeneticsbehavioral tasksdata analysisPython programming
Output against the department
Publications98bottom 33% of dept.449th of 671
this lab
most publishedleast published
Citations7.5ktop 50% of dept.334th of 671
this lab
most citedleast cited
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