Baylor College of Medicine · PhysiologyProBioMod Lab
Christine Beeton · Houston, Texas
Research Focus
Christine Beeton's lab focuses on developing innovative treatments for autoimmune diseases using engineered probiotics. The lab is working on a probiotic that delivers a specific peptide to modulate the immune response, particularly in conditions like rheumatoid arthritis. This project aims to create a non-invasive treatment option that improves patient compliance and effectiveness of therapy.
probioticsautoimmune diseasesrheumatoid arthritisimmunomodulationpeptide delivery
Research Aims
4AIM 01Evaluate the pharmacokinetics and biodistribution of an engineered probiotic.
AIM 02Assess the efficacy of a probiotic-based approach for treating rheumatoid arthritis.
AIM 03Optimize the safety of oral delivery of immunomodulatory peptides.
AIM 04Establish proof-of-concept for novel therapeutic strategies in autoimmune diseases.
Skills the Lab Values
PCRcell cultureanimal modelsflow cytometryWestern blot16S rRNA sequencingimmunohistochemistrydrug kineticsclinical trials
Output against the department
Publications125bottom 39% of dept.175th of 286
this lab
most publishedleast published
Citations6.9ktop 47% of dept.135th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.