Columbia University in the City of New York · BiologyNeuronal Health and Microtubule Dynamics Lab
Francesca Bartolini · New York, New York
Research Focus
Dr. Francesca Bartolini's lab at Columbia University focuses on understanding the mechanisms behind Alzheimer's disease and chemotherapy-induced peripheral neuropathy (CIPN). By studying how microtubule stability and tubulin modifications impact neuronal health, the lab aims to uncover new pathways that could lead to effective treatments for these conditions.
Alzheimer's diseasechemotherapy-induced peripheral neuropathymicrotubule stabilitypost-translational modificationstau hyperphosphorylationneuronal functiontubulin modifications
Research Aims
5AIM 01Investigate the role of microtubule stabilization in Alzheimer's disease pathology.
AIM 02Explore how post-translational modifications of tubulin contribute to chemotherapy-induced peripheral neuropathy.
AIM 03Examine the mechanisms behind tau hyperphosphorylation in neuronal cells.
AIM 04Identify potential therapeutic targets for mitigating cognitive decline in Alzheimer's.
AIM 05Evaluate the impact of tubulin modifications on sensory neuronal functions.
Skills the Lab Values
cell cultureimmunohistochemistryWestern blotPCRlive-cell imaginganimal modelsneurophysiology techniquesbiochemical assaysdata analysis in Rexperimental design
Output against the department
Publications96bottom 33% of dept.687th of 1,033
this lab
most publishedleast published
Citations2.8kbottom 21% of dept.819th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.