Icahn School of Medicine at Mount Sinai · NeuroscienceCenter for Depression Innovation
Helen S Mayberg · New York, New York
Research Focus
Dr. Helen S. Mayberg's lab focuses on developing innovative treatments for patients with treatment-resistant depression using a technique called deep brain stimulation (DBS). By studying how the brain's electrical signals relate to patients' moods and behaviors, the lab aims to create a method that allows doctors to make more objective treatment decisions. This research could help improve the effectiveness and personalization of depression therapies, potentially benefiting many who struggle with this condition.
deep brain stimulationtreatment resistant depressionbiomarkersclinical decision-makinglongitudinal dataneural circuitsdepression treatmentelectrophysiologyreal-time monitoring
Research Aims
5AIM 01Develop a biomarker-informed treatment decision algorithm for DBS.
AIM 02Optimize decision-making processes in treating depression.
AIM 03Test the effectiveness of a new control policy in clinical settings.
AIM 04Integrate multimodal data for improved patient outcomes.
AIM 05Assess the scalability of innovative DBS treatment strategies.
Skills the Lab Values
deep brain stimulationdata collectionelectroencephalography (EEG)positron emission tomography (PET)statistical modelinglongitudinal study designclinical assessment techniquesdata analysisbioinformatics
Output against the department
Publications535top 10% of dept.69th of 671
this lab
most publishedleast published
Citations60ktop 5% of dept.34th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.