Augusta University · PharmacologyThe AgeWell Lab
Raghavan Pillai Raju · Augusta, Georgia
Research Focus
Dr. Raghavan Pillai Raju's lab focuses on understanding how factors derived from juvenile animals can help improve health outcomes in older individuals who suffer from injuries. The research particularly examines how juvenile plasma factors can aid recovery and reduce damage after traumatic events such as hemorrhagic shock, which is a leading cause of death among the elderly. By investigating the mechanisms behind these protective factors, the lab aims to develop strategies to counteract the negative effects of aging and promote healthier aging.
agingjuvenile factorshemorrhagic shockorgan functionneurodegenerationAlzheimer's diseaseextracellular vesiclesoxidative stressplasma factorsmolecular biology
Research Aims
5AIM 01Investigate the effects of juvenile factors on recovery from hemorrhagic shock in aged mice.
AIM 02Identify how juvenile-derived extracellular vesicles improve organ function post-injury.
AIM 03Examine the mechanisms by which juvenile plasma factors reduce oxidative stress in aged organisms.
AIM 04Explore the relationship between juvenile factors and Alzheimer's disease pathology in mouse models.
AIM 05Develop therapeutic approaches to enhance recovery in elderly patients following traumatic injuries.
Skills the Lab Values
cell culturebiochemical assaysgenomic analysismicroRNA studyanimal modelingextracellular vesicle isolationflow cytometryimmunohistochemistrydata analysis with Pythonsurvival analysis
Output against the department
Publications121bottom 34% of dept.302nd of 462
this lab
most publishedleast published
Citations3.8kbottom 29% of dept.326th of 462
this lab
most citedleast cited
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