Stanford University · ChemistryKool Lab
Eric T. Kool · Stanford, California
Research Focus
Dr. Eric T. Kool's lab at Stanford University is focused on exploring the intricate interactions of RNA within cells. By developing innovative chemical tools, the lab aims to better understand how RNA functions and interacts with drugs, which could lead to advancements in RNA-based therapies. This research is crucial not only for improving our understanding of cellular processes but also for enhancing the effectiveness of existing and future medical treatments involving RNA.
RNA interactionsRNA therapeuticstranscriptome analysischemical toolsdrug-RNA binding
Research Aims
5AIM 01Develop new RNA-reactive reagents to analyze RNA interactions.
AIM 02Map the interactions of small molecule drugs with RNAs in cells.
AIM 03Create methods for functionalizing native RNAs at specific sites.
AIM 04Investigate the effects of chemical modifications in mRNA therapeutics.
AIM 05Apply advanced methodologies to understand RNA networks and their implications for health.
Skills the Lab Values
RNA sequencingchemical functionalizationcell culturefluorescent labelingcrosslinking techniqueshigh-throughput screeningmolecular cloningbiochemical assaysdata analysis using Python
Output against the department
Publications465top 20% of dept.44th of 216
this lab
most publishedleast published
Citations26ktop 17% of dept.36th of 216
this lab
most citedleast cited
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