George Washington University · GeneticsTrapnell Genomics Lab
Bruce Colston Trapnell · Washington, District of Columbia
Research Focus
Professor Bruce Trapnell's lab focuses on using advanced software tools to analyze single-cell genomics, particularly in the study of embryonic development and disease mechanisms. They work on generating and validating new datasets that provide insights into how cell types and genes function at a detailed level. By developing computational algorithms, the lab aims to better understand how genetic and environmental factors influence cell behavior in complex tissues.
single-cell genomicsembryonic developmentdisease mechanismscomputational biologysoftware tools
Research Aims
3AIM 01Develop software for analyzing shifts in cell populations across healthy and diseased states.
AIM 02Create tools to identify genes involved in cell-state transitions during development or disease.
AIM 03Establish methods to link chromatin states to transcriptional regulation.
Skills the Lab Values
ATAC-seqRNA sequencingdata visualizationalgorithm developmentzebrafish models
Output against the department
Publications315top 26% of dept.68th of 259
this lab
most publishedleast published
Citations21ktop 28% of dept.73rd of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.