Georgia Institute of Technology-Main Campus · EngineeringCancer Therapy Innovation Lab
Stanislav Y Emelianov · Atlanta, Georgia
Research Focus
Dr. Stanislav Y. Emelianov's lab at Georgia Tech focuses on enhancing cancer therapy through innovative techniques that improve the effectiveness of CAR T cell treatment for solid tumors, such as breast cancer. By using advanced imaging methods and unique gene switches that activate CAR T cells at specific temperatures, the lab aims to deliver targeted therapy while minimizing side effects. This cutting-edge research merges engineering with cancer treatment to create safer and more effective therapeutic options for patients.
CAR T cellstumor microenvironmentimmunotherapyfocused ultrasoundphotoacoustic imagingcancer therapygene therapybiologicsreal-time imagingsolid tumors
Research Aims
5AIM 01Develop a system to visualize CAR T cell infiltration in tumors using advanced imaging techniques.
AIM 02Create thermal gene switches that activate CAR T cells upon reaching specific temperatures.
AIM 03Test the effectiveness of combined imaging and therapy on breast cancer models.
AIM 04Evaluate patient safety by minimizing off-target effects of CAR T therapies.
AIM 05Investigate the application of this technology for other types of cancers beyond breast cancer.
Skills the Lab Values
photoacoustic imagingfocused ultrasoundgene engineeringcell cultureanimal modelsimmunotherapy techniquesthermal imagingbiomarker analysismicroscopydata visualization
Output against the department
Publications491top 12% of dept.32nd of 278
this lab
most publishedleast published
Citations21ktop 17% of dept.48th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.