Johns Hopkins University · GeneticsSobreira Lab
Nara Sobreira · Baltimore, Maryland
Research Focus
Dr. Nara Sobreira's lab focuses on studying Ollier disease and Maffucci syndrome, two rare conditions linked to cancer susceptibility. The lab investigates the genetic factors and biological pathways that lead to these diseases, aiming to develop new treatments for patients. By examining the phenotypic features, genetic variants, and their impact on a specific cancer-related pathway, the lab seeks to provide insights that could enhance diagnosis and therapy for these and related cancers.
Ollier diseaseMaffucci syndromecancer susceptibilityHIF-1 pathwaygenomics
Research Aims
3AIM 01Define the phenotypic features of patients with Ollier disease and Maffucci syndrome.
AIM 02Identify the genetic causes and variants associated with these diseases.
AIM 03Examine how genetic variants affect the HIF-1 pathway.
Skills the Lab Values
genomic sequencingbiobankingpatient phenotypinggenetic variant analysisfunctional assays
Output against the department
Publications106bottom 32% of dept.176th of 259
this lab
most publishedleast published
Citations4.7kbottom 25% of dept.195th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.