Indiana University-Purdue University-Indianapolis · Microbiology & ImmunologySalty Defender Lab
Martin Joseph Richer · Indianapolis, Indiana
Research Focus
Dr. Martin Joseph Richer's lab at Indiana University Indianapolis focuses on understanding how diet, specifically high salt intake, affects immune responses to viral infections. Their research investigates whether excessive salt can hinder the function of critical immune cells, particularly CD8 T cells, which play a vital role in fighting off viruses. By exploring the mechanisms involved, they aim to uncover potential therapeutic targets to improve immune function in individuals consuming high levels of dietary salt.
CD8 T cellshigh salt dietviral infectionimmune responseT cell exhaustion
Research Aims
2AIM 01Determine how high salt intake affects CD8 T cell mechanisms during viral infection.
AIM 02Identify the intrinsic factors in T cells that are impaired by excessive salt consumption.
Skills the Lab Values
cell culturemouse modelsimmunological assaysflow cytometrygene expression analysis
Output against the department
Publications72bottom 22% of dept.375th of 486
this lab
most publishedleast published
Citations3.1kbottom 22% of dept.378th of 486
this lab
most citedleast cited
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