University of Illinois Urbana-Champaign · BiologyLipid Metabolism and Cardiovascular Health Lab
Bo Wang · Champaign, Illinois
Research Focus
Dr. Bo Wang's lab focuses on understanding how certain proteins in liver cells influence the metabolism of lipids, specifically cholesterol and triglycerides. This research is essential for tackling cardiovascular diseases like atherosclerosis, which is linked to high levels of these lipids in the blood. By studying the role of the SEC16B protein, the lab aims to identify new therapeutic targets that could help reduce the risk of developing heart-related health issues.
lipid metabolismatherosclerosischolesteroltriglyceridesSEC16Bliver metabolismVLDLprotein regulationlipid droplets
Research Aims
2AIM 01Examine how SEC16B regulates lipid droplets formation in hepatocytes.
AIM 02Elucidate the function and mechanisms of action of SEC16B in VLDL metabolism in the liver.
Skills the Lab Values
cell cultureanimal modelsWestern blottingin vitro experimentsbiochemical assaysgenetic studiesliver cell isolationdata analysismolecular biology techniques
Output against the department
Publications362top 14% of dept.142nd of 1,033
this lab
most publishedleast published
Citations7.2ktop 50% of dept.520th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.