EUEmory University · Genetics
Weinshenker Lab
David Weinshenker · Atlanta, Georgia
Research Focus
Dr. David Weinshenker's lab at Emory University focuses on understanding the role of neuromelanin in the degeneration of specific neurons in Alzheimer's disease. They are particularly interested in how these changes contribute to early symptoms like anxiety and cognitive impairment. Through innovative techniques, the lab aims to uncover mechanisms that could lead to new treatments and diagnostic tools for Alzheimer's disease.
Alzheimer's diseaseneurodegenerationneuromelaninnorepinephrine neuronsbehavioral symptoms
Research Aims
3AIM 01Examine how neuromelanin affects the integrity of locus coeruleus neurons.
AIM 02Assess the impact of neuromelanin on neuron firing and gene expression.
AIM 03Identify how changes in norepinephrine synthesis affect neuromelanin accumulation and toxicity.
Skills the Lab Values
PCRmouse modelsviral vector technologyelectrophysiologyimmunohistochemistrymagnetic resonance imaging (MRI)gene expression analysisbehavioral testingchromatographytissue staining
Output against the department
Publications275top 30% of dept.77th of 259
this lab
most publishedleast published
Citations12ktop 44% of dept.113th of 259
this lab
most citedleast cited
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