University at Buffalo · Biomedical EngineeringWu Lab
Yun Wu · Buffalo, New York
Research Focus
Dr. Yun Wu's lab focuses on developing innovative methods for early lung cancer detection and monitoring patients' responses to immunotherapy treatments. By utilizing a non-invasive liquid biopsy approach called the Exo-PROS assay, the team aims to identify specific biomarkers from tumor-derived exosomes found in blood samples. This research seeks to improve the accuracy and effectiveness of lung cancer diagnostics, ultimately enhancing patient outcomes through better treatment strategies.
liquid biopsylung cancerexosomesbiomarkersimmunotherapyearly detectiondiagnostic toolsbiopsy alternativescancer treatmentnon-invasive diagnostics
Research Aims
3AIM 01Develop the Exo-PROS assay for detecting lung cancer biomarkers.
AIM 02Evaluate the diagnostic performance of the Exo-PROS assay compared to traditional methods.
AIM 03Analyze the efficacy of the Exo-PROS assay in monitoring immunotherapy responses.
Skills the Lab Values
liquid biopsy techniquesexosome isolationbiomarker analysisRNA extractionquantitative PCRclinical trial designdata analysisstatistical methodspatient care strategies
Output against the department
Publications2,357top 1% of dept.3rd of 595
this lab
most publishedleast published
Citations113ktop 1% of dept.4th of 595
this lab
most citedleast cited
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