University of California-San Francisco · PharmacologyAbate Lab
Adam R. Abate · San Francisco, California
Research Focus
Dr. Adam R. Abate's lab focuses on developing innovative diagnostic technologies to improve the identification of infectious diseases and study rare cell populations involved in conditions like multiple sclerosis. The lab combines next-generation sequencing with unique methods to enhance pathogen detection and offers insights into complex cellular mechanisms by analyzing specific cell types from samples. The goal is to provide healthcare professionals with more accurate tools for diagnosing infections and understanding related diseases.
diagnosticsinfectious diseasesmultiple sclerosisnext-generation sequencingsingle-cell analysis
Research Aims
5AIM 01Develop rapid and sensitive diagnostic tools for infectious diseases.
AIM 02Identify regulatory mechanisms in rare astrocyte subsets linked to multiple sclerosis.
AIM 03Enhance pathogen genome detection from clinical samples.
AIM 04Refine methods to characterize single cells at a genomic level.
AIM 05Improve diagnostic accuracy and treatment selection for infectious diseases.
Skills the Lab Values
next-generation sequencingPCRflow cytometrycell cultureRNA sequencingbioinformaticsdigital PCRmouse modelsmicroscopy
Output against the department
Publications243top 34% of dept.155th of 462
this lab
most publishedleast published
Citations20ktop 18% of dept.85th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.