University of Alabama at Birmingham · GeneticsWallis-Schultz Oncology Lab
Deeann Wallis-Schultz · Birmingham, Alabama
Research Focus
Dr. Deeann Wallis-Schultz's lab at the University of Alabama at Birmingham focuses on understanding how a gene called NF1 contributes to breast cancer development, particularly in hormone-sensitive cases. The lab utilizes innovative rat models that mimic human breast cancer to study how loss of this gene affects tumor growth and response to treatments. The ultimate goal is to improve cancer prognosis and develop new therapies for patients with specific NF1 mutations.
breast cancerNF1hormone signalingrat modelstumor microenvironmentestrogen receptorcancer therapyoncogenic driversmetastasis
Research Aims
3AIM 01Evaluate tumor onset and growth in NF1 deficient rat models.
AIM 02Characterize the tumor microenvironment in relation to NF1 deficiency.
AIM 03Investigate the role of hormones in the initiation and maintenance of mammary tumors.
Skills the Lab Values
histopathologymolecular characterizationimmunotherapy techniquesrat modelstumor microenvironment analysisdrug response evaluationRNA sequencinghormone signaling pathwaysgenetic analysis
Output against the department
Publications1bottom 1% of dept.257th of 259
this lab
most publishedleast published
Citations65bottom 1% of dept.256th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.