Dartmouth College · Microbiology & ImmunologyBomberger Microbiology Lab
Jennifer Melinda Bomberger · Hanover, New Hampshire
Research Focus
Dr. Jennifer Melinda Bomberger's lab at Dartmouth College focuses on understanding the interactions between bacteria and viruses in the context of cystic fibrosis. By studying how Pseudomonas aeruginosa, a harmful bacterium, survives and causes disease in the lungs of cystic fibrosis patients, the lab aims to uncover mechanisms that promote bacterial persistence and chronic infections. Their work could lead to new therapeutic strategies to combat these severe infections.
Pseudomonas aeruginosacystic fibrosisType VI secretion systembacterial biofilmsviral-bacterial co-infections
Research Aims
3AIM 01Investigate how the T6SS immunity protein TsiT regulates Pseudomonas aeruginosa biofilms.
AIM 02Analyze the evolutionary significance of tsiT gene diversity in Gram-negative organisms.
AIM 03Examine how viral infections influence the metabolic changes in respiratory epithelial cells to affect bacterial biofilms.
Skills the Lab Values
PCRcell culturemouse modelsbiofilm assaysmetabolic profilinggene expression analysismicrobial ecology techniquesimmunofluorescence microscopyRNA sequencing
Output against the department
Publications181top 37% of dept.178th of 486
this lab
most publishedleast published
Citations4.9kbottom 36% of dept.310th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.