AECAlbert Einstein College of Medicine · Biology
Hematopoietic Stem Cell Dynamics Lab
Teresa V Bowman · Bronx, New York
Research Focus
Dr. Teresa V. Bowman's lab at Albert Einstein College of Medicine investigates how genetic mutations affect the blood system, focusing particularly on conditions like myelodysplastic syndromes (MDS). By using zebrafish models, the lab explores the role of specific genes and environmental factors in the development and function of hematopoietic stem and progenitor cells, which are crucial for blood cell production. The research aims to uncover insights that could lead to better understanding and treatment of blood disorders, particularly in older adults.
hematopoietic stem cellsmyelodysplastic syndromesagingzebrafish modelsblood disordersgenetic mutationsER stressbone marrow failureinflammationimmune system
Research Aims
5AIM 01Investigate how DDX41 mutations affect hematopoietic stem and progenitor cell function during aging.
AIM 02Explore the interaction between DDX41 mutations and age-associated inflammation in blood disorders.
AIM 03Examine the differences in function between hematopoietic stem cells and progenitor cells created during development.
AIM 04Identify genetic regulators influencing hematopoietic development in zebrafish.
AIM 05Analyze connections among different cellular progenitors and their impact on blood and immune function.
Skills the Lab Values
Zebrafish modelinggene expression analysisimmunohistochemistryin vivo imaginglineage tracingPCRRNA sequencingflow cytometryWestern blotdata visualization
Output against the department
Publications135bottom 48% of dept.528th of 1,033
this lab
most publishedleast published
Citations5.7kbottom 42% of dept.598th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.