University of Michigan-Ann Arbor · Biomedical EngineeringMyelofibrosis Imaging and Therapy Lab
Brian D. Ross · Ann Arbor, Michigan
Research Focus
Dr. Brian D. Ross leads a research lab focused on improving the diagnosis and treatment of myelofibrosis, a serious blood cancer. The lab is developing advanced MRI techniques to create noninvasive biomarkers that can better monitor the disease and evaluate the effectiveness of new targeted therapies. By integrating innovative imaging methods with cutting-edge treatment strategies, they aim to enhance patient management and outcomes for those suffering from this chronic illness.
myelofibrosisMRI biomarkerstargeted therapybone marrow imaginghematologic neoplasmsJAK pathwaytreatment responsedisease monitoringnoninvasive diagnosis
Research Aims
5AIM 01Develop quantitative MRI biomarkers to assess bone marrow involvement in myelofibrosis.
AIM 02Evaluate the effectiveness of novel targeted treatments in mouse models of myelofibrosis.
AIM 03Create noninvasive imaging techniques to monitor disease progression and treatment response.
AIM 04Investigate the role of JAK and PI3K pathways in myelofibrosis treatment.
AIM 05Implement advanced imaging analysis methods to enhance disease phenotype detection.
Skills the Lab Values
magnetic resonance imaging (MRI)image processinganimal modelscellular analysisbiomarker developmentquantitative imaging techniquesdata analysis in medical researchmedication dosing and pharmacodynamicsexperimental design
Output against the department
Publications678top 9% of dept.54th of 595
this lab
most publishedleast published
Citations36ktop 6% of dept.35th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.