Columbia University in the City of New York · NeuroscienceBradshaw Lab
Elizabeth M Bradshaw · New York, New York
Research Focus
Dr. Elizabeth M Bradshaw's lab at Columbia University focuses on understanding the link between the immune system and Alzheimer's disease (AD). They investigate how genetic factors influence the immune response to HSV-1, a virus that may play a role in AD progression. By integrating genetics, immunology, and computational biology, the lab aims to uncover the mechanisms by which HSV-1 interacts with genetic predispositions to AD and affects microglial function.
Alzheimer's DiseaseHSV-1microglial geneticsimmune responseneurodegeneration
Research Aims
5AIM 01Investigate the effect of genetic background on microglial response to HSV-1 infection.
AIM 02Examine the role of microglia as antigen-presenting cells in Alzheimer's disease.
AIM 03Explore the relationship between HSV-1 infection and genetic susceptibility to Alzheimer's disease.
AIM 04Analyze immune responses in clinical and cohort studies related to Alzheimer's disease.
AIM 05Utilize cutting-edge technology to study interactions between pathogens and neurodegeneration.
Skills the Lab Values
genetic analysisimmunohistochemistrycell culturetranscriptomicscomputational biologyanimal modelsepidemiological studiesviral assaysbioinformatics
Output against the department
Publications121bottom 42% of dept.386th of 671
this lab
most publishedleast published
Citations8.6ktop 44% of dept.298th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.