University of California-Davis · BiologyAlbeck Lab
John G. Albeck · Davis, California
Research Focus
Dr. John G. Albeck's lab at UC Davis focuses on understanding how individual cells manage their metabolism, particularly through glycolysis, the process by which glucose is broken down for energy. They use advanced live-cell measurements to explore how different cells in tissues like muscle and liver can vary in their metabolic activities. This research aims to unveil the links between metabolism and other cell functions, such as growth and death, which could lead to new insights into diseases like diabetes and cancer.
glycolysiscell metabolismdiabetescancerlive-cell imagingcellular heterogeneitymetabolic modeling
Research Aims
3AIM 01Determine how glycolytic rates vary among individual cells using live-cell measurements.
AIM 02Link glycolytic activity to protein synthesis rates through AKT, AMPK, and mTOR signaling.
AIM 03Develop a mathematical model to integrate glycolytic flux with signaling network regulation.
Skills the Lab Values
live-cell microscopymultiplexed measurementscell culturemathematical modelingdata analysisfluorescence microscopyNADH/NAD+ measurementkinase activity assayscellular signaling pathways
Output against the department
Publications113bottom 40% of dept.619th of 1,033
this lab
most publishedleast published
Citations7.0kbottom 48% of dept.536th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.