Columbia University in the City of New York · Microbiology & ImmunologyFarber Immunology Lab
Donna L. Farber · New York, New York
Research Focus
Dr. Donna L. Farber's lab focuses on understanding how regulatory T cells (Tregs) contribute to immune memory and protection against viral infections in human tissues. They explore the unique roles of Tregs in maintaining tissue homeostasis and tolerance, investigating how these cells interact with other immune and structural cells. This research is crucial for developing therapies for autoimmune diseases and improving tissue repair and transplantation outcomes.
regulatory T cellsimmune memoryviral infectionshuman tissuesimmunoregulation
Research Aims
3AIM 01Investigate the role of antigen and tissue in memory Treg induction
AIM 02Define the clonal and migratory relationships between memory Tregs and other memory subsets
AIM 03Examine the functional interactions of tissue Tregs with immune and structural cells in lymph nodes.
Skills the Lab Values
T cell profilingsingle-cell RNA sequencingtissue cultureflow cytometryimmunohistochemistry
Output against the department
Publications338top 13% of dept.62nd of 486
this lab
most publishedleast published
Citations28ktop 12% of dept.57th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.