University of Colorado Boulder · ChemistryLiu Lab
Xuedong Liu · Boulder, Colorado
Research Focus
Dr. Xuedong Liu's research lab focuses on developing innovative delivery systems called gectosomes for transporting macromolecules like proteins and RNA into specific cells. These gectosomes are designed to overcome the limitations of current delivery methods, making it safer and more efficient for applications in gene editing and therapeutic research. The lab aims to enhance the targeting precision, safety, and scalability of these delivery systems in order to advance functional genomics and epigenetic studies.
gectosomesmacromolecule deliverygene editingfunctional genomicstherapeutic research
Research Aims
4AIM 01Develop optimal producer cell lines for guide RNA expression.
AIM 02Engineer viral glycoproteins for targeted cell delivery.
AIM 03Implement controllable release mechanisms for drug cargo.
AIM 04Scale up manufacturing using advanced bioreactor systems.
Skills the Lab Values
cell culturebioreactor operationaffinity chromatographyprotein engineeringRNA manipulationlipid nanoparticle formulationviral vector designelectroporationanalytical techniques
Output against the department
Publications326top 34% of dept.74th of 216
this lab
most publishedleast published
Citations13ktop 39% of dept.84th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.