University of Miami · Microbiology & ImmunologyFrasca Lab
Daniela Frasca · Coral Gables, Florida
Research Focus
Dr. Daniela Frasca's research focuses on understanding how aging and HIV affect the immune system, specifically looking at the metabolic changes that occur in immune cells. The lab studies how these changes can lead to poorer immune responses and aims to develop strategies to improve immunity in aging individuals living with HIV. By exploring the links between metabolism, inflammation, and immune function, this research could help enhance the health of older adults with HIV.
agingHIVimmune dysfunctioninflammationmetabolismB cellsT cellssenolyticsmetabolic modifiersgut microbiome
Research Aims
3AIM 01Evaluate how aging influences the metabolic profile of people living with HIV.
AIM 02Investigate metabolic mechanisms affecting the function of immune cells in aging individuals with HIV.
AIM 03Use metabolic modifiers to enhance immune cell function in vitro.
Skills the Lab Values
PCRcell cultureflow cytometrymass spectrometrybioelectrical impedance analysisgene expression analysisin vitro experimentationdata analysisimmune profilingbiochemical assays
Output against the department
Publications272top 19% of dept.93rd of 486
this lab
most publishedleast published
Citations10ktop 35% of dept.172nd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.