Columbia University in the City of New York · NeuroscienceAgalliu Neurobiology Lab
Dritan Agalliu · New York, New York
Research Focus
Dr. Dritan Agalliu's lab at Columbia University focuses on understanding traumatic brain injury (TBI) and its effects on the brain's blood-barrier system. Using advanced human cell models, particularly stem cells, the lab investigates how immune responses and blood components impact brain function after injury. They aim to develop innovative models that can help identify new biomarkers for TBI and test potential treatments to mitigate its effects.
traumatic brain injuryblood-brain barrieriPSCneurovascular unitimmune response3D modelsbrain organoidsvascularizationbiomarkerstherapeutics
Research Aims
3AIM 01Generate and characterize iPSC-derived cells that form a neurovascular unit.
AIM 02Establish and validate a 3D perfused blood-brain barrier model with human cells.
AIM 03Analyze the impact of blood components on blood-brain barrier function after TBI.
Skills the Lab Values
human induced pluripotent stem cell (iPSC) cultureimmunofluorescence3D cell culturetranscriptomicsmicroscopyvascularization techniquesblood component analysiscell signaling studiesbrain-on-a-chip technologyorganoid development
Output against the department
Publications82bottom 24% of dept.508th of 671
this lab
most publishedleast published
Citations6.3kbottom 43% of dept.382nd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.