Johns Hopkins University · BiologyRobinson Mechanosensing Lab
Douglas N Robinson · Baltimore, Maryland
Research Focus
Douglas N Robinson's lab at Johns Hopkins University investigates how cells respond to mechanical forces through their cytoskeletal structures. By studying how cells sense and adapt to their physical environment, the lab aims to uncover the mechanisms behind cellular processes like division and movement, which are fundamental for development and health. The research leverages unique model organisms, advanced imaging techniques, and innovative computational models to explore these fascinating interactions.
mechanosensingcytoskeletoncell behaviorDictyosteliumcell divisionmyosin IImechanical forcescontractility kitsbiochemical modeling
Research Aims
5AIM 01Investigate how mechanical forces influence cytoskeletal assembly and disassembly.
AIM 02Explore the role of nonmuscle myosin II in cellular behavior and dynamics.
AIM 03Develop predictive computational models for mechanosensitivity in cells.
AIM 04Test the mechanics of protein assemblies under varying force conditions.
AIM 05Analyze the impact of mechanosensing on cell division and gene expression.
Skills the Lab Values
cell culturemicroscopymass spectrometrymagnetic tweezerscomputational modelingRNA extractionprotein purificationscattering techniquesstochastic simulations
Output against the department
Publications211top 31% of dept.315th of 1,033
this lab
most publishedleast published
Citations6.0kbottom 44% of dept.583rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.