West Virginia University · BiochemistryPhotoreceptor Therapeutics Laboratory
Visvanathan Ramamurthy · Morgantown, West Virginia
Research Focus
Dr. Visvanathan Ramamurthy's lab focuses on developing therapies for vision loss caused by defects in photoreceptor outer segments. These segments are critical for our ability to see, and when they don't develop correctly, it can lead to blindness. The lab studies a specific protein called Prominin-1, which has been linked to several eye diseases, and seeks to find ways to treat conditions associated with mutations in this protein.
photoreceptorsouter segment developmentgene therapyretinal diseasesblindness therapies
Research Aims
2AIM 01Identify the optimal therapeutic regimen for PROM1-associated blindness
AIM 02Uncover mechanisms of PROM1's role in outer segment morphogenesis
Skills the Lab Values
AAV-mediated gene therapyelectrophysiologyimmunoprecipitationbiochemical analysisproteomicslight microscopyanimal modelselectroretinography
Output against the department
Publications84bottom 18% of dept.329th of 402
this lab
most publishedleast published
Citations2.2kbottom 8% of dept.370th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.