University of Illinois Urbana-Champaign · EngineeringHarley Biomaterials Lab
Brendan A. Harley · Champaign, Illinois
Research Focus
Dr. Brendan A. Harley's lab focuses on developing advanced biomaterials to study two significant areas: the generation of blood and immune cells from stem cells in the bone marrow and the mechanisms driving the initiation of endometriosis lesions. By creating tissue engineering models that mimic the body's natural processes, the lab aims to enhance our understanding of hematopoiesis and endometrioma formation. This research has important implications for improving treatments for blood disorders and endometriosis, which are major health issues.
hematopoiesisendometriosistissue engineeringbiomaterialsstem cells
Research Aims
5AIM 01Investigate how dynamic matrix signals influence hematopoietic stem cell fate.
AIM 02Develop a tissue engineering model to study endometrioma initiation.
AIM 03Examine the impact of mesenchymal stem cell remodeling on hematopoietic activity.
AIM 04Analyze the role of ovarian microenvironment in endometrioma invasion.
AIM 05Evaluate the effects of hypoxia on hematopoietic stem cell behavior.
Skills the Lab Values
microfluidicscell culturebiomaterial development3D printinghypoxia modeling
Output against the department
Publications327top 25% of dept.69th of 278
this lab
most publishedleast published
Citations11ktop 34% of dept.94th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.