Columbia University in the City of New York · Microbiology & ImmunologyGhosh Inflammation Lab
Sankar Ghosh · New York, New York
Research Focus
Dr. Sankar Ghosh's lab focuses on understanding the underlying mechanisms of diseases like Inflammatory Bowel Disease and Alzheimer's Disease. By investigating genetic factors and molecular pathways, the lab aims to identify potential therapeutic targets. Through studies on long noncoding RNAs and mitochondrial function, they seek to reveal how these elements contribute to disease susceptibility and progression.
Inflammatory Bowel DiseaseAlzheimer's Diseaselong noncoding RNAECSITmitochondrial functionChronic inflammationgenetic risk factorsneurodegenerationimmune response
Research Aims
5AIM 01Characterize the role of long noncoding RNA in Inflammatory Bowel Disease.
AIM 02Investigate the involvement of ECSIT in Alzheimer’s Disease.
AIM 03Understand how SNPs affect long noncoding RNA expression in IBD.
AIM 04Elucidate the mechanisms of T cell regulation by long noncoding RNA.
AIM 05Test the mitochondrial cascade hypothesis in models of neurodegeneration.
Skills the Lab Values
RNA purificationanimal modelsmolecular biology techniquesimmunofluorescencegenetic studiesWestern blotCRISPR gene editingcell cultureflow cytometry
Output against the department
Publications259top 21% of dept.104th of 486
this lab
most publishedleast published
Citations71ktop 2% of dept.10th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.