Icahn School of Medicine at Mount Sinai · BiologyThe Hematopoietic Nexus
Christopher Michael Sturgeon · New York, New York
Research Focus
Dr. Christopher Sturgeon's lab focuses on understanding how blood cells develop in embryos, particularly how different early cell types contribute to the formation of blood and immune cells. By studying these early developmental processes, the lab aims to improve techniques for generating various blood cell types from stem cells, which could have significant applications in regenerative medicine and treatments for blood disorders. Their work investigates the roles of different cellular programs and signaling mechanisms in hematopoietic development.
hematopoietic stem cellsembryonic developmentblood cell differentiationhemogenic mesodermregenerative medicine
Research Aims
5AIM 01Understand the origins of different hematopoietic programs
AIM 02Investigate how hemogenic mesoderm gives rise to hematopoietic stem cells
AIM 03Explore the clinical applications of embryonic hematopoietic cell types
AIM 04Characterize the transcriptional mechanisms regulating hematopoiesis
AIM 05Develop methods to generate blood cells from patient-derived stem cells
Skills the Lab Values
human pluripotent stem cell culturedirected differentiation techniquesimmunophenotypinggene expression analysissignal transduction assays